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Foreword (Ronald T. Borchardt). Preface. PART I. TRANSFORMING PROTEINS AND GENES INTO THERAPEUTICS. Introduction to Biopharmaceuticals. Development of Drugs that are Proteins and Genes Versus Small Molecules. Biotechnology Industry Perspective on Drug Development. Biopharmaceutical Technologies and Processes in Drug Development. Pharmacology, Toxicology, Therapeutic Dosage Formulations and Clinical Responses. Hematopoietic Growth Factors and Coagulation Factors. Interferon and Cytokines for Anti-Infective and Cancer Therapy. Hormones. Enzymes. Antibodies and Derivatives. Vaccines Shiu-Lok HuOther Products. PART III. FUTURE DIRECTIONS. Advanced Drug Delivery. Individualization of Drug Regimens: Integration of Pharmacokinetic and Pharmacognetic Principles in Drug Therapy. Gene and Cell Therapy. Integration of Discovery and Development: The Role Genomics and Proteomics. Appendix I. Pharmacokinetics and Disposition Data. Appendix II. Molecular Characteristic and Therapeutic Use. Appendix III. Nomenclature of Biotechnology Products. Appendix IV. Synonym of Trade, Common, and Scientific Names of Biotechnology Products. Appendix V. Other Information.