Table of contents for Liquid chromatography-mass spectrometry : an introduction / Robert E. Ardrey.

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Series Preface.
Preface.
Acknowledgements .
Acronyms, Abbreviations and Symbols.
About the author.
1. Introduction.
What are the advantages of linking HPLC with mass spectrometry?
What capabilities are required of the combination?
What problems, if any, have to be addressed to allow the LC-MS combination to function and function effectively?
2. Chromatography.
Introduction.
High Performance Liquid Chromatography.
Chromatographic properties.
Identification using HPLC.
Quantitation using HPLC.
The need for LC-MS.
3. Mass spectrometry.
Introduction.
Mass Spectrometry.
Summary.
4. Interface Technology.
Introduction.
The moving belt interface.
The direct liquid introduction interface.
The continuous Flow/Frit (Dynamic) Fast Atom Bombardment interface.
The particle beam interface.
The thermospray interface.
The electrospray interface.
The atmospheric pressure chemical ionization (APCI) interface.
5. Applications of LC-MS.
Method Development.
The molecular weight determination of biopolymers.
Structure determination of biopolymers.
Molecular weight determination of small (< 1000 Da) molecules.
The structure determination of low molecular weight compounds.
Quantitation.
Summary.
Responses to Self-Assessment Queries.
Bibliography.
Glossary of Terms.
Period Table.
Index.