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Introduction. Biomaterials: Structure and Properties. Proteins. Protein-Surface Interactions. Blood-Biomaterial Interactions: Coagulation. Inflammation and Infection. The Immune System and Inflammation. Wound Healing. Biomaterial Surface and the Physiological Environment. Biocompatibility. Example 1: Opening Occluded Vessels: Vascular Grafts, Intimal Hyperplasia. Example 2: Replacing Joints and Teeth. Gloassry.