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An Introduction to Applied Probability. Assessing Significance in a Fourfold Table. Determining Sample Sizes Needed to Detect a Difference Between Two Proportions. How to Randomize. Sampling Method I: Naturalistic or Cross-Sectional Studies. Sampling Method II: Prospective and Retrospective Studies. Sampling Method III: Controlled Comparative Trials. The Analysis of Data from Matched Samples. Comparison of Proportions from Several Independent Samples. Combining Evidence from Fourfold Tables. Effects of Misclassification Errors. Control of Misclassification Error. Measurement of Inter-rate Agreement. Standardization of Rates. Appendixes. Answers to Numerical Problems. Indexes.