Table of contents for The kinetochore : from molecular discoveries to cancer therapy / Peter De Wulf, William C. Earnshaw, editors.


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1 Centromeres and Kinetochores: An Historical Perspective .........  1
Kerry S. Bloom
2 The Basics of Chromosome Segregation. ......................  21
Mitsuhiro Yanagida
3  The  Centrom ere  .........................................  45
Beth A. Sullivan
4  Neocentromeres  ..................  ......................  77
Owen J. Marshall and K.H. Andy Choo
5 Human Artificial Centromeres: De novo Assembly of Functional
Centromeres on Human Artificial Chromosomes ................ 107
Hiroshi Masumoto, Teruaki Okada, and Yasuhide Okamoto
6 Kinetochore Composition, Formation, and Organization .......... 133
Tatsuo Fukagawa and Peter De Wulf
7  Evolution of Centromeres and Kinetochores: A Two-Part
Fugue.................................................     193
Paul B. Talbert, Joshua J. Bayes, and Steven Henikoff
8 Mitotic Spindle Assembly Mechanisms ....................... 231
Rebecca Heald and Claire E. Walczak
9  Kinetochore-Microtubule Interactions ........................  269
Lesley Clayton and Tomoyuki U. Tanaka
10  Post-Translational Modifications that Regulate Kinetochore
Activity. ................... ........ ......   .........  293
Chitra V. Kotwaliwale and Sue Biggins
11 The Role of the Kinetochore in Spindle Checkpoint Signaling ...... 345
P. Todd Stukenberg and Daniel J. Burke
12 Kinetochore Regulation of Anaphase and Cytokinesis ............ 371
Scott Thomas and Kenneth B. Kaplan
13 Roles of Centromeres and Kinetochores in Meiosis .............. 395
Adele L. Marston
14  The Kinetochore-Cancer Connection  .........................  433
Takeshi Tomonaga
15 The Kinetochore as Target for Cancer Drug Development ......... 455
Song-Tao Liu and Tim J. Yen



Library of Congress subject headings for this publication: Chromosomes, Cell organelles