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I What Is a Stem Cell Niche? S.-I. Nishikawa, M. Osawa . .. . .......... 1 2 New Strategy for Comprehensive Analysis of Gene Functions in Embryonic Stem cells J. Takeda, K. Horie, K. Yusa ... ... ... .... 15 Paternal Dual Barrier by Ifg2-H19 and Dlkl-Gtl2 to Parthenogenesis in Mice . Kono, M. Kawahara, Q. Wu, H. Hiura, Y Obata . 23 4 Cell-Cell Fusion as a Means to Establish Pluripotency IT. Do, H.R. Scholer ............ . 35 5 Toward Reprogramming Cells to Pluripotency P Collas, C.K. Taranger ...... . . . . 47 6 Molecular Switches and Developmental Potential of Adult Stem Cells M. Zenke, T7 Hieronymus . ............... 69 7 Adult Small Intestinal Stem Cells Identification, Location, Characteristics, and Clinical Applications C.S. Potten, J.R. Elis .. .... . . ... . 81 8 Tracking Sten Cells In Vivo R. Yoneyama, E.R. Chenaly, .J. Hajjar . 99 9 Establishment of Nuclear Transfer Embryonic Stem Cell Lines from Adult Somatic Cells by Nuclear Transfer and Its Application Ti Wakayama .. . . . ..... ........ . l 10 Derivation of Germ Cells from Embryonic Stem Cells J. Kehler, K. Hiibneier H.R. Scholer ........ . 125 11 Germline Recruitment in Mice: A Genetic Program for Epigenetic Reprogramming Y Ohinata, Y. Seki, B. Payer D. O'Carroll, M.A. Surani, AM Saitou . ........ . . .. .... . 43 t2 Transplantation of Germ Line Stem Cells for the Study and Manipulation of Spermatogenesis L Dobrinski ... . . . . . .. 175 13 Progenitor Cell-Based Myelination as a Model for Cell-Based Therapy of the Central Nervous System S.A. Goldman, J. Lang, N. Roy S.J Schanz, FS. S, S. Wang, V Washco, M.S. Windren ... ..... .. 195 14 Adult Neural Stem Cells and Central Nervous System Repair HI Okano . . . ... . ... .. . 215 15 Stem Cell Therapy for Parkinsons Disease J Ihkahashi .u . . . .. .. 229 Previous Volumes Published in This Series ....... . 245