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1 An Introduction to R 1 1.1 What Is R? 1 1.2 Installing R 2 1.3 Help and Documentation 4 1.4 Data Objects in R 5 1.5 Data Import and Export 9 1.6 Basic Data Manipulation 11 1.7 Simple Summary Statistics 14 1.8 Organising an Analysis 18 1.9 Summary 20 "2 Simple Inference 21 2.1 Introduction 21 2.2 Statistical Tests 25 2.3 Analysis Using R 29 2.4 Summary 39 3 Conditional Inference 41 3.1 Introduction 41 3.2 Conditional Test Procedures 44 3.3 Analysis Using R 46 3.4 Summary 53 4 Analysis of Variance 55 4.1 Introduction 55 4.2 Analysis of Variance 58 4.3 Analysis Using R 59 4.4 Summary 71 5 Multiple Linear Regression 73 5.1 Introduction 73 5.2 Multiple Linear Regression 74 5.3 Analysis Using R 76 5.4 Summary 85 6 Logistic Regression and Generalised Linear Models 89 6.1 Introduction 89 6.2 Logistic Regression and Generalised Linear Models 92 6.3 Analysis Using R 94 6.4 Summary 106 7 Density Estimation 109 7.1 Introduction 109 7.2 Density Estimation 111 7.3 Analysis Using R 117 7.4 Summary 125 8 Recursive Partitioning 131 8.1 Introduction 131 8.2 Recursive Partitioning 131 8.3 Analysis Using R 133 8.4 Summary 141 9 Survival Analysis 143 9.1 Introduction 143 9.2 Survival Analysis 144 9.3 Analysis Using R 150 9.4 Summary 157 10 Analysing Longitudinal Data I 159 10.1 Introduction 159 10.2 Analysing Longitudinal Data 162 10.3 Linear Mixed Effects Models 163 10.4 Analysis Using R 165 10.5 Prediction of Random Effects 168 10.6 The Problem of Dropouts 169 10.7 Summary 172 11 Analysing Longitudinal Data II 175 11.1 Introduction 175 11.2 Generalised Estimating Equations 177 11.3 Analysis Using R 179 11.4 Summary 194 12 Meta-Analysis 197 12.1 Introduction 197 12.2 Systematic Reviews and Meta-Analysis 199 12.3 Statistics of Meta-Analysis 201 12.4 Analysis Using R 202 12.5 Meta-Regression 203 12.6 Publication Bias 207 12.7 Summary 211 13 Principal Component Analysis 215 13.1 Introduction 215 13.2 Principal Component Analysis 215 13.3 Analysis Using R 218 13.4 Summary 223 14 Multidimensional Scaling 227 14.1 Introduction 227 14.2 Multidimensional Scaling 227 14.3 Analysis Using R 233 14.4 Summary 239 15 Cluster Analysis 243 15.1 Introduction 243 15.2 Cluster Analysis 245 15.3 Analysis Using R 248 15.4 Summary 253