Table of contents for An introduction to toxicogenomics / edited by Michael E. Burczynski.

Bibliographic record and links to related information available from the Library of Congress catalog. Note: Electronic data is machine generated. May be incomplete or contain other coding.


SECTION 1  Fundamentals of Expression Profiling Analysis
Chapter 1
Preparation and Utilization of Microarrays.........................................................3
Sophie Wildsmith and Fiona Spence
Chapter 2
Comparative Studies Using cDNA vs. Oligonucleotide Arrays ........................................17
Jiang Li and Jeffrey A. Johnson
Chapter 3
Quality  Control of Expression  Profiling  Data...................................................29
Andrew Hill and Maryann Whitley
Chapter 4
An Introduction to Cluster Analysis ..............................................................45
Frederick Immermann and Youping Huang
SECTION 2          Expression Profiling and Toxicology:
The Advent of Toxicogenomics
Chapter 5
Transcriptional Profiling in Toxicology...........................................................81
Julia Scheel, Marie-Charlotte von Brevern, and Thorsten Storck
SECTION 3 Model Systems in Toxicogenomic Studies
Chapter 6
Microarrays in Drug Metabolism and Toxicology: 
Rat Liver Responses to Prototypical CYP Inducers ...... ............................   ........ 101
David Gerhold, Jian Xu, and Thomas Rushmore
Chapter 7
Characterization of Hepatocytes and Their Use as a Model System in Toxicogenomics ...........117
Thomas K. Baker, Marnie A. Higgins, Mark A. Carfagna, and Timothy P Ryan



SECTION 4            Mechanistic Toxicogenomics
Chapter 8
Molecular Signatures of Dioxin Toxicity  .......................................................147
J. Kevin Kerzee, Craig R. Tomlinson, Jennifer L. Marlowe, and Alvaro Puga
Chapter 9
Toxicogenomic Dissection of the Antioxidant Response............................................163
Jiang Li and Jeffrey A. Johnson
Chapter 10
An Overview of Mechanistic Toxicogenomic Studies ...............................................183
Julia Scheel, Marie-Charlotte von Brevern, and Thorsten Storck
SECTION 5 Predictive Toxicogenomics
Chapter 11
Gene Expression Profile Databases in Toxicity Testing ..........................................213
Robert T Dunn II and Kyle L. Kolaja
Chapter 12
Predictive Toxicogenomics  .....................................................................225
Mark W Porter, Arthur L. Castle, Michael S. Orr, and Donna L. Mendrick
Chapter 13
Unsupervised Hierarchical Clustering of Toxicants...............................................261
Jeffrey F Waring and Roger G. Ulrich
Chapter 14
Toxicogenomic Analysis in Clinical Pharmacogenomic Studies......................................285
Michael E. Burczynski
SECTION 6 The Future of Toxicogenomics
Chapter 15
The Future of Toxicogenomics .................................................................. 299
John C. Rockett
INDEX .......................................................................... .............. 319