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List of contributors
Preface
H. Vaudry and A. Arimura
1 PACAP: Discovery, Gene, Receptors
A. Arimura
2 Molecular Evolution of PACAP Precursor
and PACAP Receptors
B.K.C. Chow, R.T.K. Pang and S.S.M. Ng
3 Development of Selective Ligands for PAC1,
VPAC1 and VPAC2 Receptors
P. Robberecht, P. Vertongen, I. Langer and J. Perret
4 Molecular Pharmacology and Structure-Function
Analysis of PACAP/VIP Receptors
M. Laburthe, A. Couvineau and P. Nicole
5 PACAP Receptor Signaling
S. Shioda, C.J.I. Zhou and H. Ohtaki and T. Yada
6 Function of PACAP in the Central Nervous System
B.J. Gonzalez, D. Vaudry, M. Basille, C. Rousselle,
A. Falluel-Morel and H. Vaudry
7 Function of PACAP in the Hypothalamo-Pituitary
Complex
M.Malagon, J.P. Castaiio, S. Garcia-Navarro,
A.J. Martinez-Fuentes and F. Gracia-Navarro
8 PACAP in the Endocrine Pancreas
B. Ahren
9 Function of PACAP in the Adrenal Cortex
G.G. Nussdorfer
10 PACAP : An 'Emergency Response' Co-Transmittter
in the Adrenal Medulla
C. Hamelink, E. Weihe and L.E. Eiden
11 PACAP in the Urogenital Tract
J. Fahrenkrug, J. Hannibal and S. Gras
12 Function of PACAP in the Cardiovascular System
A. Miyata
13 Function of PACAP in the Respiratory System
J.C. Prieto
14 Function of PACAP in the Immune System
M. Delgado, J. Leceta and R.P. Gomariz
15 PACAP Receptor Knockout and Transgenics.
What Have We Learnt?
P. Brabet, F. Jamen, N. Rodriguez-Henche, G. Bertrand
and J. Bockaert
16 Consequences of PACAP Gene Knockout
N.M. Sherwood, S.L. Gray and K.J. Cummings
17 The Biological Significance of PACAP and PACAP
Receptors in Human Tumors : From Cell Lines
to Cancers
V. Lelievre, N. Pineau and J.A. Waschek