Table of contents for Introduction to proteomics : tools for the new biology / by Daniel C. Liebler ; foreword by John R. Yates, III.

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Foreword  by J. R. Yates, III .................................................    v
Preface ................................................................................ vii
I.  Proteomics and  the Proteome  .........................................................1
   1. Proteomics and the New Biology .........................................................3
   2. The Proteome ........................................................................ 15
II. Tools of Proteomics .................................................................... 25
   3. Overviewof Analytical Proteomics........................................27
   4. Analytical Protein and Peptide Separations .....................................31
   5. Protein Digestion Techniques ...........................................................49
   6. Mass Spectrometersfor Protein and Peptide Analysis .....................55
   7. Protein Identification by Peptide Mass Fingerprinting ....................77
   8. Peptide Sequence Analysis by Tandem Mass Spectrometry...............................89
   9. Protein Identification with Tandem Mass Spectrometry Data .............................99
  10. SALSA: An Algorithmfor Mining Specific Features of Tandem MS Data ....................109
III.  Applications of Proteomics .........................................123
  11. Mining Proteomes ...................................................................125
  12. Protein Expression Profiling  .................................................... 137
  13. Identifying Protein-Protein Interactions and Protein Complexes ..................... 151
  14. Mapping Protein Modifications ...................................................... 167
  15. New Directions in Proteomics .........................................................185
Index ......................................................................................................... 195