Table of contents for Oxford handbook of clinical pharmacy / Philip Wiffen ... [et al.].

Bibliographic record and links to related information available from the Library of Congress catalog.

Note: Contents data are machine generated based on pre-publication provided by the publisher. Contents may have variations from the printed book or be incomplete or contain other coding.


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Contents
Contributors xi
Acknowledgements xiii
Detailed contents xv
Symbols and abbreviations xxv
1 Adherence 1
2 Adverse drug reactions and drug interactions 13
3 Anaphylaxis 29
4 Clinical pharmacy skills 35
5 Clinical trials 113
6 Controlled drugs 127
7 Evidence-based medicine 131
8 Herbal medicines 161
9 Medical gases 185
10 Patient management issues 191
11 Patient-specific issues 217
12 Pharmaceutical calculations 249
13 Pharmaceutical care 257
14 Policy 271
15 Research 315
16 Therapy-related issues 329
Appendices 591
Index 615
Contributor
Mark Borthwick
Lead Pharmacist, Critical Care Oxford Radcliffe Hospitals NHS Trust, UK, wrote six monographs on critical care.
Acknowledgements
We are grateful to the following people who provided comments and help:
John Beale, Sarah Cripps, Mrudula Patel, Rhoda Welsh, and Rebecca White.
We are also grateful to the following reviewers:
Jon Hayhurst, Phil Rogers, and Nicola Walker.
Detailed contents
Contributors xi
Acknowledgements xiii
Symbols and abbreviations xxv
1 Adherence 1
 Introduction 2 
 Assessing adherence 4 
 Strategies to improve adherence 6 
 Adherence counselling 8 
 Writing patient information leaflets 10 
2 Adverse drug reactions and drug interactions 13
 Introduction 14 
 Classification of adverse drug reactions (ADRs) 16 
 Adverse reactions: drug or disease? 18 
 Helping patients understand the risk of ADRs 20 
 Reporting ADRs 22 
 Drug interactions 24 
 Managing drug interactions 28 
3 Anaphylaxis 29
 Symptoms and signs 30 
 Treatment of anaphylaxis 32 
 Prevention of anaphylaxis 34 
 
Detailed contents
4 Clinical pharmacy skills 35
 Guidelines for prescription endorsement of hospital or institutional drug charts by pharmacists 36 
 Prescription screening and monitoring 40 
 Writing on medicine (drug) charts 44 
 Understanding medical notes 46 
 Writing in medical notes 54 
 Medication review 56 
 Intervention monitoring 60 
 Drug-history (DHx) taking 62 
 Drug-use evaluation (DUE) 64 
 Dealing with mistakes 66 
 Financial reports and budget statements 68 
 Hospital budget statements 70 
 Writing reports 72 
 Using medicines information services 78 
 Ward etiquette 80 
 Assertiveness 82 
 Communication skills 84 
 Dealing with medical staff 88 
 Patient etiquette 90 
 Dealing with aggressive or violent patients 92 
 Dealing with distressed patients 94 
 Dealing with dying patients 96 
 What if your patient is dead in the bed? 100 
 Managing meetings 102 
 Oral presentation skills 104 
 Prioritizing 106 
 Project planning 108 
 Time management 108 
 Ethical dilemmas 110 
5 Clinical trials 115
 Definitions 116 
 Licensing 118 
 European directive 120 
 Clinical trials and the European directive: hospital pharmacy guidance 122 
 Ethical committees 124 
 Pharmacists advising ethics committees 126 
6 Controlled drugs 127
 Suspected loss of controlled drugs within 
hospitals 128 
 Patient's own controlled drugs in a hospital setting 130 
7 Evidence-based medicine 131
 Evidence-based medicine and clinical pharmacy 132 
 Statistical versus clinical significance 134 
 Odds ratios and relative risk 136 
 Binary and continuous data 138 
 L'Abbé plots 140 
 Mean difference and the standardized mean difference 142 
 Assessing the quality of randomized studies 144 
 Critical appraisal of systematic reviews 146 
 Critical assessment of papers 148 
 Bandolier's knowledge library for pharmacy 152 
 The number needed to treat (NNT) 154 
 Confidence intervals 158 
8 Herbal medicines 161
 Herbal medicinal products of current interest 162 
 Herbal drugs 164 
 Chinese herbal medicine 168 
 Herbal interactions 170 
 Perioperative considerations for herbal drugs 174 
9 Medical gases 185
 Clinical uses 186 
 Cylinder identification coding 188 
10 Patient management issues 191
 Drug use in liver disease 192 
 Drug dosing in liver disease 194 
 Hepatorenal syndrome (HRS) 198 
 Drugs in renal impairment 200 
 Drugs in pregnancy 206 
 Drugs in breastfeeding 210 
 Glucose 6-phosphate dehydrogenase (G6 PD) deficiency 214 
11 Patient-specific issues 217
 Medicines for children: introduction 218 
 Medicines for children: pharmacodynamics and pharmacokinetics 220 
 Medicines for children: licensing 222 
 Medicines for children: calculating children's doses 224 
 Medicines for children: adherence 226 
 'Pill school': teaching children how to take tablets and capsules 228 
 Medicines for elderly people: introduction 230 
 Medicines for elderly people: medication review 234 
 Dealing with injecting drug users in hospital 236 
 Discharge prescriptions for opioid-replacement therapy 242 
 Surgical patients and nil-by-mouth (NBM) issues 244 
12 Pharmaceutical calculations 249
 Concentrations 250 
 Moles and millimoles 252 
 Practical issues involving pharmaceutical calculations 254 
 Pharmaceutical calculations involving drug administration 256 
13 Pharmaceutical care 257
 The concept of pharmaceutical care 258 
 Core elements of pharmaceutical care 260 
 Medication problem checklist 262 
 Pharmaceutical care economics 264 
 Staffing 266 
 Standards for research 268 
14 Medicines management 271
 Medicines management 272 
 Evaluating new drugs 274 
 How to write a drug protocol 276 
 Unlicensed use of medicines 278 
 Drug and therapeutics committees 280 
 Patient group directions 282 
 Supplementary prescribing 284 
 Community (FP10) prescription use in hospitals 288 
 Electronic prescribing 290 
 Incident reporting 292 
 Medical representatives 294 
 Overseas visitors 296 
 Private patients 298 
 Professional supervision skills 300 
 National Service Frameworks (NSFs) 302 
 Appraisal 304 
 Confidentiality 306 
 Gene therapy 308 
 Standards of business conduct for clinical pharmacists 310 
 Disposal of medicines 312 
15 Research 315
 Audit and research 316 
 Personal bibliographic databases 318 
 Writing a research proposal 322 
 Citations in documents and articles for publication 326 
16 Therapy-related issues 329
 Diarrhoea 330 
 Constipation in adults 332 
 Management of nausea and vomiting 336 
 Angina 340 
 Tolerance to nitrate therapy 344 
 Heart failure 346 
 Drug interventions for severe heart failure 352 
 Acute cardiogenic pulmonary oedema 354 
 Treatment of hypertension 358 
 Understanding anticoagulation 360 
 Clinical use of anticoagulants 362 
 Warfarin dosing 368 
 Counselling patients treated with warfarin 370 
 Out-patient anticoagulation clinics 372 
 Acute coronary syndromes 374 
 ST-segment elevation myocardial infarction (STEMI) 376 
 Drug treatment in acute coronary syndromes 382 
 Cardiopulmonary resuscitation 386 
 Asthma management in adults: British Thoracic Society and SIGN guidelines 392 
 Inhaler techniques 394 
 Pain: a definition 398 
 Assessment of pain 400 
 Acute pain: incidence 404 
 Acute pain 406 
 Treating cancer pain 408 
 Equianalgesic doses for opioids 410 
 Compatibility of drugs in pain and palliative care 412 
 Chronic pain 414 
 Basic microbiology 418 
 Modes of action of antibacterials 422 
 Selection and use of antimicrobials 424 
 Antimicrobial prophylaxis 436 
 Optimizing antimicrobial use 438 
 Antimicrobial prescribing guidelines 440 
 Antimicrobial resistance 444 
 Infection control 448 
 Diabetes mellitus 452 
 Monitoring and control 454 
 Policy for the administration and handling of cytotoxic drugs 456 
 Clinical screening of chemotherapy prescriptions 460 
 Chemotherapy dosing 464 
 Antiemetics for the prophylaxis of chemotherapy-induced nausea and vomiting 468 
 Principles of extravasation 476 
 Extravasation of chemotherapy in adult patients 478 
 Treatment of chemotherapy drug extravasations in adults patients 484 
 Extravasation of chemotherapy in paediatric patients 494 
 Common toxicity criteria (CTC) 496 
 Intrathecal administration of chemotherapy 498 
 Administration sets 502 
 Intravenous (IV) administration pumps and other devices 504 
 Guidelines for the treatment of hypomagnesaemia 508 
 Treatment guidelines for hypophosphataemia 510 
 Parenteral potassium 512 
 Guidelines for the treatment of hypocalcaemia 516 
 Prescribing IV fluids 518 
 Fluid balance 522 
 Practical issues concerning parenteral nutrition 526 
 Nutritional support in adults 530 
 Normal nutritional requirements 532 
 Children's parenteral nutrition regimens 536 
 Enteral feeding 542 
 Drug administration in patients with feeding tubes 546 
 IV therapy at home 548 
 Sodium content of parenteral drugs 554 
 Wound care 558 
 Introduction to critical care 564 
 Mechanical ventilation 568 
 Motility stimulants 570 
 Renal-replacement therapy 572 
 Stress-ulcers: prophylaxis 576 
 Vasoactive agents 578 
 Treatment of alcohol withdrawal 582 
 Dealing with poisoning enquiries 586 
 Drug desensitization 588 
 Appendices 591
 Pathology ranges and interpretation 592 
 Normal ranges 600 
 Paediatric Normal laboratory values 602 
 Drug Interference with laboratory tests 606 
 Therapeutic drug monitoring (TDM in adults) 608 
 Useful websites 612 
 Index 615 

Library of Congress Subject Headings for this publication:

Clinical pharmacology -- Handbooks, manuals, etc.
Pharmacy -- Handbooks, manuals, etc.
Pharmacology, Clinical -- methods -- Handbooks.
Pharmaceutical Services -- Handbooks.