Table of contents for Bioinorganic chemistry : a short course / edited by Rosette M. Roat-Malone.

Bibliographic record and links to related information available from the Library of Congress catalog.

Note: Contents data are machine generated based on pre-publication provided by the publisher. Contents may have variations from the printed book or be incomplete or contain other coding.


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Table of Contents
Bioinorganic Chemistry: A Second Short Course
Rosette M. Roat-Malone
Chapter 1: Inorganic Chemistry Essentials
Introduction 
Essential Chemical Elements
Metals in Biological Systems: A Survey
Inorganic Chemistry Basics
Biological Metal Ion Complexation
	Thermodynamics
	Kinetics
Electronic and Geometric Structures of Metals in Biological Systems
Bioorganometallic Chemistry
Electron Transfer
Introduction to Biological Metal Homeostasis, Transport, and Storage
Chapter 2: Biochemistry Fundamentals
Introduction
Proteins
	Amino Acid Building Blocks
	Protein Structure
	Protein Sequencing and Proteomics
	Protein Function, Enzymes and Enzyme Kinetics
Nucleic Acids
	DNA and RNA Building Blocks
	DNA and RNA Molecular Structures
	Transmission of Genetic Information
	Genetic Mutations and Site-Directed Mutagenesis
	Genes and Cloning
	Genomics and the Human Genome
The ATP-binding cassette (ABC) Transporter Superfamily
Chapter 3: Instrumental Methods
Introduction
	Analytical Instrument-Based Methods
	Spectroscopy
X-ray Absorption Spectroscopy (XAS) and Extended X-ray Absorption Fine Structure (EXAFS)
	Theoretical Aspects and Hardware
	Descriptive Examples
X-ray Crystallography
	Introduction
	Crystallization and Crystal Habits
	Theory and Hardware
	Descriptive Examples
Electron Paramagnetic Resonance
	Theory and Determination of g-values
	Hyperfine and Superhyperfine Interactions
	Descriptive Examples
Nuclear Magnetic Resonance
	Theoretical Aspects
	Nuclear Screening and the Chemical Shift
	Spin-Spin coupling
	Techniques of Spectral Integration and Spin-Spin Decoupling
 Nuclear Magnetic Relaxation
	The nuclear Overhauser Effect (NOE)
 Obtaining the NMR spectrum
	Two-dimensional NMR Spectroscopy
	Correlation Spectroscopy (COSY)
	Nuclear Overhauser Effect Spectroscopy (NOESY)
	Descriptive Examples
M¿ssbauer Spectroscopy
	Theoretical Aspects
	Quadrupole Splitting and the Isomer Shift
	Magnetic Hyperfine Interactions
	Descriptive Examples
Atomic Force Microscopy
Fast Methods
	Stopped-Flow Kinetic Methods
	Flash Photolysis
	Time-Resolved Crystallography
Chapter 4: Introduction to Computer-Based Methods
Computer Hardware 
Molecular Modeling and Molecular Mechanics
	Introduction to MM
	Molecular Modeling, Molecular Mechanics and Molecular Dynamics
	Biomolecule Modeling
	Molecular Modeling Descriptive Examples
Quantum Mechanics-Based Computational Methods
	Introduction
	Ab-initio Methods
	Density Functional Theory
	Semi-empirical Methods
Computer Software for Chemistry
	Mathematical Software
World Wide Web Online Resources
	Nomenclature and Visualization Resources
	Online Societies, Literature, Materials, Equipment Webservers
Chapter 5: Group I and II metals in biological systems
Transport and storage of metal ions
Homeostasis involving Na+, K+, Ca2+, Mg2+, Zn2+ (as well as P, Cl, and H)
Movement of molecules and ions across membranes
	Proton pumps
	Ion pumps
	Active versus passive transport 
Na+/ K+ ATPases
Magnesium dependent biomolecules
	Kinases
	ATP-pumps
	Catalytic RNA and Magnesium
	Magnesium in chlorophyll
Calcium dependent biomolecules
	Calmodulins and triggering
Biochemistry of nitrogen oxides, nitroxyl, and peroxynitrite ion
Chapter 6: Iron Containing Proteins and Enzymes 
Iron-containing proteins with porphyrin ligand systems
 Hemoglobin and Myoglobin (first edition material somewhat condensed)
 Cytochrome P-450: a monooxygenase
 Iron-containing cytochromes in photosynthesis
		Green plant cytochromes
			Cytochrome bc559
			Cytochrome bf
		Bacterial cytochromes
			Cytochrome c2
			Cytochrome bc1
 Iron-containing cytochromes in the respiratory pathway
		Cytochrome c
		Cytochrome c oxidase
Non-Heme Iron-containing proteins
	MMO-Methane Monooxygenase
	Catechol dioxygenases
	Iron-oxo clusters
		Transferrin for metal transport 
 Ferritin for metal storage
 Hemerythrin
 Purple acid phosphatase
	Iron-sulfur cluster proteins
		Rubredoxin
		Ferrodoxins
		Aconitase
Chapter 7: Enzymes containing zinc, nickel, and enzymes with multiple metal cofactors
Zinc homeostasis, transport, and storage
Zinc Enzymes
	Alkaline phosphatase
	Alcohol dehydrogenase
	Aspartate transcarbamoylase
	Carbonic anhydrase
	Carboxypeptidase A and B
	Zinc Fingers
Nickel Enzymes
 Urease
 F430
Enzymes with multiple metal cofactors
 Hydrogenases
	Carbon monoxide dehydrogenases
		
Chapter 8 Disease, Disease Diagnosis and Treatment Utilizing Inorganic Species
Metal Transport and Metallochaperones
Disease States
	Metal deficiency
	Metal toxicity
		Copper toxicity
		FALS
		Wilson and Menkes diseases
Disease Diagnosis
	Technetium Imaging Agents
	Gadolinium MRI Imaging Agents
	Quantum Dots for In vivo Imaging
Metals in Medicine
	Manganese superoxide mimetics
	Vanadium-based Diabetes Drugs
	Platinum-containing Anticancer Agents
Nanomedicine

Library of Congress Subject Headings for this publication:

Bioinorganic chemistry.
Biochemistry.
Chemistry, Bioinorganic.