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Contents Preface Acknowledgements Sources of illustrations Section 1: Introduction 1 Overview of the cardiovascular system Section 2: Anatomy and histology 2 Gross anatomy and histology of the heart 3 Vascular anatomy 4 Vascular histology and smooth muscle cell ultrastructure Section 3: Blood and body fluids 5 Constituents of blood 6 Erythropoiesis, haemoglobin and anaemia 7 Haemostasis and thrombosis 8 Blood groups and transfusions Section 4: Biochemistry and cellular physiology 9 Membrane potential, ion channels and pumps 10 Electrophysiology of cardiac muscle and the origin of the heart beat 11 Excitation-contraction coupling in cardiac muscle cells 12 Vascular smooth muscle excitation-contraction coupling Section 5: Form and function 13 Cardiac cycle 14 Control of cardiac output and Starling's Law of the Heart 15 Electrical conduction system in the heart 16 The electrocardiogram 17 Haemodynamics 18 Blood pressure and flow in the arteries and arterioles 19 The microcirculation and the lymphatic system 20 Fluid filtration in the microcirculation 21 The venous system 22 Local control of bloodflow 23 Regulation of the vasculature by the endothelium 24 The coronary, skeletal muscle, cutaneous and cerebral circulations 25 The pulmonary and fetal circulations Section 6: Integration and regulation 26 Cardiovascular reflexes 27 Autonomic control of the cardiovascular system 28 The control of blood volume 29 Cardiovascular effects of exercise 30 Shock and haemorrhage Section 7: History, examination and investigations 31 History and examination of the cardiovascular system 32 Cardiovascular investigations Section 8: Pathology and therapeutics 33 Pharmacology of the cardiovascular system 34 Risk factors for cardiovascular disease 35 Hyperlipidaemias 36 Atherosclerosis 37 Treatment of hypertension 38 Mechanisms of primary hypertension 39 Stable and variant angina 40 Unstable angina and non-ST segment elevation myocardial infarction 41 Pharmacological management of stable and variant angina 42 Revascularisation 43 Pathophysiology of acute myocardial infarction 44 Clinical aspects of acute myocardial infarction 45 Thrombosis, anticoagulants and thrombolytics 46 Chronic heart failure 47 Treatment of chronic heart failure 48 Mechanisms of arrhythmia 49 Pharmacological treatment of arrhythmias 50 Supraventricular tachyarrhythmias 51 Ventricular tachyarrhythmias and nonpharmacological treatment of arrhythmias 52 Diseases of the aortic valve 53 Diseases of the mitral valve 54 Congenital heart disease Section 9: Self-assessment case studies Case studies and questions Answers Index
Library of Congress Subject Headings for this publication:
Cardiovascular system -- Physiology.
Cardiovascular system -- Pathophysiology.
Cardiovascular System -- anatomy & histology.
Cardiovascular Diseases.
Cardiovascular Physiology.