Table of contents for Heat shock proteins in neural cells / [edited by] Christiane Richter-Landsberg.

Bibliographic record and links to related information available from the Library of Congress catalog.

Note: Contents data are machine generated based on pre-publication provided by the publisher. Contents may have variations from the printed book or be incomplete or contain other coding.


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		Preface	ix
	1.	Heat Shock Proteins: Expression and Functional Roles 
in Nerve Cells and Glia	1
Christiane Richter-Landsberg
Introduction	1
Heat Shock Proteins in Nerve Cells and Glia	4
Concluding Remarks	8
	2.	Small Heat Shock Proteins and the Cytoskeleton: 
Their Role in Inclusion Body Formation in Glial Cells	13
Christiane Richter-Landsberg and Olaf Goldbaum	
Introduction	13
The Cytoskeleton in Nerve Cells and Glia	14
Interaction of Small Heat Shock Proteins 
with Cytoskeletal Proteins	15
sHSPs and Inclusion Body Formation in Glial Cells	19
Concluding Remarks	20
	3.	The Role of Hsps in Neuronal Differentiation and Development	25
Kate Reed Herbert, Afshin Samali and Adrienne Gorman
Introduction	25
Hsp Expression during Development of the Nervous System	26
Transcriptional Regulation of Hsp Expression during Neuronal Development and Differentiation
	28
Possible Roles of Hsps in Neuronal Differentiation 
and Development of the Nervous System	28
Concluding Remarks	33
	4.	Heme Oxygenase as a Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress 
Response: Role of Acetylcarnitine	39
Vittorio Calabrese, Giovanni Pennisi, Menotti Calvani, 
D. Allan Butterfield, Cesare Mancuso and Anna Maria Giuffrida Stella
Introduction	39
Heme Oxygenase-1	40
HO-1, Oxidative Stress and Neurodegenerative Disorders	43
Acetylcarnitine	45
Conclusions and Perspectives	47
	5.	Heat Shock Proteins and the Regulation of Apoptosis	53
Una FitzGerald, Adrienne M. Gorman and Afshin Samali
Introduction to Apoptosis	53
Hsp27 and Hsp70, the Anti-Apoptotic Heat Shock Proteins	55
Apoptosis, Hsps and Neurodegenerative Disorders	58
Concluding Remarks	62
	6.	Assembly of Protein Aggregates in Neurodegeneration: 
Mechanisms Linking the Ubiquitin/Proteasome Pathway 
and Chaperones	67
Sha-Ron Pierre, Vita Vernace, Zhiyou Wang 
and Maria E. Figueiredo-Pereira
Introduction	67
Protein Degradation by the UPP	68
Potential Mechanisms for the Formation 
of Ubiquitin-Protein Aggregates	71
Subcellular Distribution of Ubiquitin-Protein Aggregates	75
Concluding Remarks	76
	7.	The Role of Heat Shock Proteins during Neurodegeneration 
in Alzheimer's, Parkinson's and Huntington's Disease	81
Andreas Wyttenbach and Andr¿ Patrick Arrigo
Introduction	81
Common Mechanisms Leading to Impaired Neuronal Function 
and Death and the Role of HSPs	88
Heat Shock Proteins and Therapy	96
Conclusions	97
	8.	Heat Shock Proteins in Multiple Sclerosis	101
Celia F. Brosnan, Luca Battistini and Krzysztof Selmaj
Introduction	101
The Small Heat Shock Proteins	102
The HSP60 Family	104
The HSP70 Family	106
Concluding Remarks	108
		Index	113

Library of Congress Subject Headings for this publication:

Heat shock proteins.
Nerve tissue proteins.
Neurons.
Neuroglia.
Heat-Shock Proteins.
Neurons -- physiology.
Neuroglia -- physiology.