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Contributing Authors Preface I. HISTORY AND DEFINITIONS 1. Historical Background of Discoid and Systemic Lupus Erythematosus Thomas G. Benedek 2. The Definition and Classification of Systemic Lupus Erythematosus Zuhre N Tutuncu, Kenneth C Kalunian 3. Environmental Aspects of Lupus Frederick W. Miller and Glinda S. Cooper 4. The Epidemiology of Systemic Lupus Erythematosus Violeta Rus, Erinn E. Maury and Marc C. Hochberg II. PATHOGENESIS 5. The Pathogenesis of Systemic Lupus Erythematosus Bevra H Hahn 6. The Genetics of Human Lupus Betty P. Tsao and Hui Wu 7. The Genetics of Murine Systemic Lupus Erythematosus Dwight H. Kono and Argyrios N. Theofilopoulos 8. Apoptosis David A. Martin, Keith B. Elkon 9. The Interaction of T Cells with Cells of the Innate Immune System and B Cells in the Pathogenesis of SLE David A. Horwitz and J. Dixon Gray 10. Cytokines and Interferons in Lupus Mary K. Crow and Kyriakos A. Kirou 11. B cells in Systemic Lupus Erythematosus Stamatis-Nick C. Liossis and George C. Tsokos 12. Abnormalities in Immune Complex Clearance and Fc_ Receptor Function Jane E. Salmon 13. Complement and Systemic Lupus Erythematosus Chau-Ching Liu, Joseph M. Ahearn 14. Mechanisms of Acute Inflammation and Vascular Injury in Systemic Lupus Erythematosus H. Michael Belmont, Steven B. Abramson 15. Idiotypes and Idiotype Networks Bevra Hannahs Hahn, Fanny M. Ebling, Jatinderpal K. Kalsi 16. The Importance of Sex Hormones in Systemic Lupus Erythematosus Sara E. Walker 17. Neuroendocrine Immune Interactions: Principles and Relevance to Systemic Lupus Erythematosus Heather E Gorby, Esther M. Sternberg 18. Animal Models of Systemic Lupus Erythematosus Bevra Hannahs Hahn and Ram Raj Singh 19. Pathogenesis of Atherosclerosis in Lupus Maureen McMahon, Jennifer Grossman 20. Autoantigens and Defects in Immune Tolerance in Lupus Ram Raj Singh and Shweta Dubey III. AUTOANTIBODIES 21. The Structure and Derivation of Antibodies and Autoantibodies Giovanni Franchin, Chaim Putterman, Betty Diamond 22. Antinuclear Antibodies: An Overview Ian Giles, David Isenberg 23. Antibodies to DNA Bevra Hannahs Hahn and Betty P. Tsao 24. Antibodies to Histones and Nucleosome-Related Antigens Robert L. Rubin and Marvin J. Fritzler 25. Antibodies to Ro/SSA and La/SSB Morris Reichlin and John B. Harley 26. Antibodies to Spliceosomal Components Carol S. Lutz and Judith A. James 27. The Lupus Anticoagulant and Antiphospholipid Antibodies Gale A. McCarty 28. Clinical Application of Serologic Abnormalities in Systemic Lupus Erythematosus Francisco P. Quismorio, Jr. IV. THE SKIN IN LUPUS 29. Pathomechanisms of Cutaneous Lupus Erythematosus Jan P. Dutz, Richard D. Sontheimer, Victoria P. Werth 30. Lupus-Specific Skin Disease (Cutaneous LE) Richard D. Sontheimer, Daniel P. McCauliffe 31. Lupus--Nonspecific Skin Disease Melissa I. Costner and Richard D. Sontheimer V. CLINICAL ASPECTS OF LUPUS 32. The Clinical Presentation of Systemic Lupus Erythematosus Daniel J. Wallace 33. The Musculoskeletal System Daniel J. Wallace 34. Cardiovascular manifestations of lupus Kathleen Maksimowicz-McKinnon and Susan Manzi 35. Pulmonary Manifestations of Systemic Lupus Erythematosus David D'Cruz, Munther Khamashta, Graham Hughes 36. Clinical Aspects of Vasculitis and Selected Cutaneovascular Manifestations of Systemic Lupus Erythematosus Daniel J. Wallace 37. The Nervous System Sterling G. West 38. Psychopathology of Lupus and Neuroimaging John G. Hanly, Antonina Kuznetsova, John D. Fisk 39. Head and Neck Findings in Systemic Lupus Erythematosus: Manifestations Involving the Eye, Ear, and Larynx Robert Fox, Paul Michelson, Daniel J. Wallace 40. Ocular, Aural, and Oral Manifestations Andre Barkhuizen, Lyndell Lim, Dennis Trune, James T. Rosenbaum 41. Hematologic and Lymphoid Abnormalities in Systemic Lupus Erythematosus Francisco P. Quismorio, Jr. 42. Gastrointestinal and Hepatic Manifestations David S. Hallegua and Daniel J. Wallace 43. Systemic Lupus Erythematosus in Childhood and Adolescence Thomas J. A. Lehman 44. Drug-Induced Lupus Robert L. Rubin 45. Infections in Systemic Lupus Erythematosus Ellen M. Ginzler and Olga Dvorkina 46. Serum and Plasma Protein Abnormalities and Other Clinical Laboratory Determinations in Systemic Lupus Erythematosus Daniel J. Wallace 47. Clinical Indices in the Assessment of Lupus Jennifer Grossman and Caroline Gordon 48. Clinical Application of Serologic Abnormalities in Systemic Lupus Erythematosus Francisco P. Quismorio, Jr. 49. Differential Diagnosis and Disease Associations Daniel J. Wallace 50. Mixed Connective Tissue Disease and Overlap Syndromes Robert W. Hoffman 51. The Mother in Systemic Lupus Erythematosus George A. Karpouzas and Rodanthi C. Kitridou 52. The Fetus in Systemic Lupus Erythematosus Rodanthi C. Kitridou and T. Murphy Goodwin 53. Neonatal Lupus Jill P. Buyon and Robert M. Clancy 54. Reproductive Issues in Women with Autoimmune Disease T. Flint Porter, D. Ware Branch 55. Lupus Nephritis: Pathology and Pathogenesis Vivette D. D'Agati, Gerald B. Appel 56. Clinical and Laboratory Features of Lupus Nephritis Mary Anne Dooley VI. THE MANAGEMENT OF LUPUS 57. Principles of Therapy and Local Measures Daniel J. Wallace 58. Nonsteroidals and salicylates for Systemic Lupus Erythematosus Arash A. Horizon and Michael H. Weisman 59. Antimalarial Therapies Daniel J. Wallace 60. Systemic Glucocorticoid Therapy in Systemic Lupus Erythematosus Kyriakos A. Kirou, and Dimitrios T. Boumpas 61. Immunosuppressive Drug Therapy W. Joseph McCune, Wendy Marder, Mona Riskalla 62. Nonpharmacologic and Complementary Therapeutic Modalities Daniel J. Wallace 63. Fibromyalgia in SLE and the use of Complementary and Alternative Medicine in SLE R. Swamy Venuturupalli 64. Hormones and Gender-Related Issues Joan T. Merrill, Jill P. Buyon 65. Clinical and Management Aspects of the Antiphospholipid Antibody Syndrome Michelle Petri 66. Additional Therapies Used in the Management of Lupus Daniel J. Wallace 67. Adjunctive Measures and Issues: Allergies, Antibiotics, Vaccines, and Disability Daniel J. Wallace 68. Issues in Drug Development in SLE: Clinical Trial Design, Outcome Measures, and Biomarkers Vibeke Strand 69. Prognosis, Mortality, and Morbidity in Systemic Lupus Erythematosus Dafna D. Gladman, Murray B. Urowitz 70. Biologics and Stem Cell Therapies for Lupus Daniel J Wallace and Bevra H Hahn Appendix I. A Patient's Guide to Lupus Erythematosus Daniel J. Wallace, Bevra Hannahs Hahn, Francisco P. Quismorio, Jr. Appendix II. Lupus Resources Compiled by Jenny Allan
Library of Congress Subject Headings for this publication:
Systemic lupus erythematosus.
Lupus erythematosus.
Lupus Erythematosus, Discoid.
Lupus Erythematosus, Systemic.