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Contents Contributors vii About the Editor ix Part I. Introduction 1. Postmortem Forensic Toxicology 1 Barry Levine 2. Human Performance Toxicology Gary W. Kunsman 3. Forensic Drug Testing Amanda J. Jenkins 4. Pharmacokinetics and Pharmacodynamics Vina Spiehler and Barry Levine Part II. Methodologies 5. Specimen Preparation Theodore J. Siek 6. Spectrophotometry Kenneth Cole and Barry Levine 7. Chromatography David T. Stafford 8. Immunoassay Michael L. Smith 9. Mass Spectrometry John Cody 10. Methods Validation John Jemionek Part III. Analytes 11. Alcohol Barry Levine and Yale H. Caplan 12. Benzodiazepines Rebecca A. Jufer-Phipps and Barry Levine 13. Gamma-Hydroxybutyric Acid (GHB) Marc LeBeau 14. Central Nervous System Depressants Barry Levine 15. Opioids Sarah Kerrigan and Bruce A. Goldberger 16. Cocaine Daniel S. Isenschmid 17. Marijuana Marilyn A. Huestis 18. Amphetamines/Sympathomimetic Amines Karla A. Moore 19. Hallucinogens Amanda J. Jenkins 20. Therapeutic Drugs I: Anticonvulsant and Antiarrhythmic Drugs Barry Levine 21. Therapeutic Drugs II: Antidepressant Drugs William H. Anderson 22. Therapeutic Drugs III: Neuroleptic (Antipsychotic) Drugs Timothy L. Lacy and James H. Nichols 23. Carbon Monoxide/Cyanide Gary W. Kunsman and Barry Levine 24. Inhalants Larry A. Broussard 25. Metals Joseph J. Saady Index Contributors William H. Anderson, Ph.D. Washoe County Sheriff¿s Office¿ Forensic Science Reno, Nevada Larry A. Broussard, Ph.D. Louisiana State University Medical Center Department of Medical Technology New Orleans, Louisiana Yale H. Caplan, Ph.D. National Scientific Services, Inc. Baltimore, Maryland John Cody, Ph.D. Air Force Drug Testing Laboratory Brooks City-Base, Texas Kenneth Cole, Ph.D. Naval Research Lab Detachment Aberdeen Proving Grounds, Maryland Bruce A. Goldberger, Ph.D. University of Florida College of Medicine Gainesville, Florida Marilyn A. Huestis, Ph.D. Division of Intramural Research National Institute on Drug Abuse Baltimore, Maryland Daniel Isenschmid, Ph.D. Wayne County Medical Examiner¿s Office Detroit, Michigan John Jemionek, Ph.D. Office of the Armed Forces Medical Examiner Rockville, Maryland Amanda J. Jenkins, Ph.D. Cuyahoga County Coroner¿s Office Cleveland, Ohio Rebecca A. Jufer-Phipps, Ph.D. Office of the Chief Medical Examiner Baltimore, Maryland Sarah Kerrigan, Ph.D. College of Criminal Justice and Department of Chemistry Sam Houston State University Huntsville, Texas Gary W. Kunsman, Ph.D. Oakland County Medical Examiner Pontiac, Michigan Timothy L. Lacy, M.D. Tufts University School of Medicine Bay State Medical Center Springfield, Massachusetts Barry Levine, Ph.D. Office of the Chief Medical Examiner Baltimore, Maryland Karla A. Moore, Ph.D. Drug Enforcement Administration Alexandria, Virginia James H. Nichols, Ph.D. Tufts University School of Medicine Bay State Medical Center Springfield, Massachusetts Joseph J. Saady, Ph.D. Division of Forensic Science Richmond, Virginia Theodore Siek, Ph.D. Analytic Bio-Chemistries Feasterville, Pennsylvania Michael L. Smith, Ph.D. Office of the Armed Forces Medical Examiner Rockville, Maryland Vina Spiehler, Ph.D. Spiehler & Associates Newport Beach, California David T. Stafford, Ph.D. Memphis, Tennessee About the Editor Barry Levine, Ph.D., is Chief Toxicologist, Office of the Chief Medical Examiner, State of Maryland, and a Forensic Toxicologist, Armed Forces Medical Examiner. He is also Clinical Associate Professor, Department of Pathology at the University of Maryland School of Medicine. Dr. Levine is a diplomate of the American Board of Forensic Toxicology and the American Board of Clinical Chemistry¿Toxicological Chemistry.
Library of Congress Subject Headings for this publication:
Forensic Medicine -- methods.
Substance Abuse Detection -- methods.
Toxicology -- methods.