Table of contents for Biological aging : methods and protocols / edited by Trygve O. Tollefsbol.

Bibliographic record and links to related information available from the Library of Congress catalog.

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Preface	v
Contributors	xi
	1	Techniques for Analysis of Biological Aging
Trygve O. Tollefsbol	1
	2	Aging Cell Culture: Methods and Observations
Sharla M. O. Phipps, Joel B. Berletch, Lucy G. Andrew, 
and Trygve O. Tollefsbol	xxx
	3	Methods to Detect Biomarkers of Cellular Senescence: 
The Senescence-Associated _-Galactosidase
Koji Itahana, Judith Campisi, and Goberdhan P. Dimri	xxx
	4	Methods of Cell Sorting of Young and Senescent Cells
Joao F. Passos and Thomas von Zglinicki	xxx
	5	Telomere Length Analysis
Andres Canela, Peter Klatt, and Maria A. Blasco	xxx
	6	A Method to Detect DNA Methyltransferase I Gene Transcription 
In Vitro in Aging Systems
Joel B. Berletch, Lucy G. Andrews, and Trygve O. Tollefsbol	xxx
	7	A Method to Study the Expression of DNA Methyltransferase 
in Aging Systems In Vitro
Joel B. Berletch, Sharla M. O. Phipps, Sabrina L. Walthall, 
Lucy G. Andrews, and Trygve O. Tollefsbol	xxx
	8	The Chronological Life Span of Saccharomyces cerevisiae
Paola Fabrizio and Valter D. Longo	xxx
	9	Caloric Restriction and Life-span Determination of Yeast Cells
Oliver Medvedik and David A. Sinclair	xxx
	10	Methods of Nutrigenomics and Longevity Studies in Drosophila: 
Effects of Diets High in Sucrose, Palmitic Acid, Soy, or Beef
Jiatao Ye, Xiangqin Cui, Ann Loraine, Kerry Bynum, 
Nam Chul Kim, Gregory White, Maria De Luca, 
Mark D. Garfinkel, Xiangyi Lu, and Douglas M. Rudin	xxx
	11	Caloric Restriction Mimetics: A Novel Approach 
for Biogerontology
Mark A. Lane, George S. Roth, and Donald K. Ingram	xxx
	12	Extension of Cell Life-Span Using Exogenous Telomerase
Mo K. Kang and No-Hee Park	xxx
	13	Inducing Cellular Senescence Using Defined Genetic Elements
Hiroshi Nakagawa and Oliver G. Opitz	xxx
	14	Methods of Induction of Cellular Senescence 
Using Oxidative Stress
Jian-Hua Chen, Susan E. Ozanne, and C. Nicholas Hales	xxx
	15	Nuclear Transfer Methods to Study Aging
Lin Liu and David L. Keefe	xxx
	16	Use of Ribozymes in Cellular Aging Research
Custer C. Deocaris, Sunil C. Kaul, Kazunari Taira, 
and Renu Wadhwa	235
	17	Methods of Evaluation of Pharmacological Drugs' Effects 
on Aging and Life Span in Mice
Vladimir N. Anisimov, Irina G. Popovich, 
and Mark A. Zabezhinski	xxx
	18	Identifying Genes That Extend Life-Span 
Using a High-Throughput Screening System
Cuiying Chen and Roland Contreras	xxx
	19	Application of DNA Microarray Technology 
to Gerontological Studies
Sergey V. Anisimov	xxx
	20	Detection and Analysis of Somatic Mutations 
at a LacZ Reporter Locus in Higher Organisms: 
Application to Mus musculus and Drosophila melanogaster
Ana Maria Garcia, Rita A. Busuttil, Armando Rodriguez, 
Carlos Cabrera, Martha Lundell, Martijn E. T. Dolle, 
and Jan Vijg	xxx
	21	Subtractive Hybridization Techniques 
to Study Cellular Senescence
Michal B. Sternberg and Shimon Gepstein	xxx
	22	Mapping Genetic Polymorphisms Affecting Natural Variation 
in Drosophila Longevity
Maria De Luca and Jeff Leips	xxx
	23	Quantitative Trait Locus (QTL) Mapping in Aging Systems
Hui-Chen Hsu, Lu Lu, Nengjun Yi, Gary Van Zant, 
Robert W. Williams, and John D. Mountz	xxx
	24	2D Gel Proteomics: An Approach to Study Age-Related Differences 
in Protein-Abundance or -Isoform Complexity 
in Biological Samples
Helen Kim, Shannon Eliuk, Jessy Deshane, Sreelatha Meleth, 
Todd Sanderson, Anita Pinner, Gloria Robinson, 
Landon Wilson, Marion Kirk, and Stephen Barnes	xxx
	25	Metabolomics in the Study of Aging and Caloric Restriction
Bruce S. Kristal, Yevgeniya I. Shurubor, Rima Kaddurah-Daouk, 
and Wayne R. Matson	xxx
Index	xxx

Library of Congress Subject Headings for this publication:

Aging -- Physiological aspects -- Laboratory manuals.
Longevity -- Laboratory manuals.
Aging -- physiology -- Laboratory Manuals.
Biological Markers -- Laboratory Manuals.
Cell Aging -- physiology -- Laboratory Manuals.