Table of contents for Joslin's diabetes mellitus.

Bibliographic record and links to related information available from the Library of Congress catalog.

Note: Contents data are machine generated based on pre-publication provided by the publisher. Contents may have variations from the printed book or be incomplete or contain other coding.


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Contents
Preface	v
Contributors	vii
 1.	The History of Diabetes	1
	Donald M. Barnett and Leo P. Krall 
SECTION I: BASIC MECHANISMS OF ISLET DEVELOPMENT 
AND FUNCTION	19
 2.	Development of the Endocrine Pancreas	21
	Ondine Cleaver and Douglas A. Melton
 3.	Islets of Langerhans: Morphology and 
Postnatal Growth	41
	Susan Bonner-Weir
 4.	Genetic Regulation of Islet Function	53
	Michael S. German
 5.	Insulin Biosynthesis, Processing, and Chemistry	65
	Christopher J. Rhodes, Steven E. Shoelson, and Philippe A. Halban
 6.	Cell Biology of Insulin Secretion	83
	Jean-Claude Henquin
 7.	Insulin Secretion In Vivo	109
	Melissa K. Cavaghan and Kenneth S. Polonsky
SECTION II: HORMONE ACTION AND THE REGULATION 
OF METABOLISM	125
8.	Hormone-Fuel Interrelationships: Fed State, 
Starvation, and Diabetes Mellitus	127
	Neil B. Ruderman, Martin G. Myers, Jr., Stuart R. Chipkin, 
and Keith Tornheim
 9.	The Molecular Mechanism of Insulin Action and 
the Regulation of Glucose and Lipid Metabolism	145
	C. Ronald Kahn and Alan R. Saltiel
10.	 Insulin-like Growth Factors	169
	Karen C. McCowen and Robert J. Smith
11.	Glucagon and Glucagon-like Peptides	179
	Joel F. Habener and Timothy J. Kieffer
12.	Magnetic Resonance Spectroscopy Studies of 
Liver and Muscle Glycogen Metabolism in Humans	195
	Roy Taylor and Gerald I. Shulman
13.	Biology of Adipose Tissue	207
	Sheila Collins, Rexford S. Ahima, and Barbara B. Kahn
14.	Biology of Skeletal Muscle	227
	Alison C. Jozsi and Laurie J. Goodyear
15.	Regulation of Hepatic Glucose Metabolism	243
	Daryl K. Granner and Donald K. Scott
16.	Fat Metabolism in Diabetes	265
	Ananda Basu and Michael D. Jensen
17.	Alterations in Protein Metabolism in 
Diabetes Mellitus	275
	Craig S. Stump and K. Sreekumaran Nair
18.	Rodent Models for the Study of Diabetes	291
	Clayton E. Mathews and Edward H. Leiter
SECTION III: DIABETES: DEFINITION, GENETICS, 
AND PATHOGENESIS	329
19.	Definition, Diagnosis, and Classification of 
Diabetes Mellitus and Glucose Homeostasis	331
	Peter H. Bennett and William C. Knowler
20.	Epidemiology of Diabetes Mellitus	341
	James H. Warram and Andrzej S. Krolewski
21.	Genetics of Type 1 Diabetes	355
	Helena Reijonen and Patrick Concannon
22.	Genetics of Type 2 Diabetes	371
	Alessandro Doria
23.	Type 1 Diabetes Mellitus	399
	George S. Eisenbarth
24.	Insulin Resistance and Its Role in the 
Pathogenesis of Type 2 Diabetes	425
	Meredith Hawkins and Luciano Rossetti
25.	 b-Cell Dysfunction in Type 2 Diabetes 
Mellitus	449
	Jack L. Leahy
26.	Maturity-Onset Diabetes of the Young	463
	Andrew T. Hattersley
27.	Secondary Forms of Diabetes	477
	Om P. Ganda
28.	Syndromes of Extreme Insulin Resistance	493
	Allison B. Goldfine and Alan C. Moses
29.	Diabetes in Minorities in the United States	505
	A. Enrique Caballero
30.	Diabetes-A Worldwide Problem	525
	Paul Zimmet and Jonathan Shaw
SECTION IV: OBESITY AND LIPOPROTEIN DISORDERS	531
31.	Obesity	533
	Eleftheria Maratos-Flier and Jeffrey S. Flier
32.	Treatment of Obesity	547
	Xavier Pi-Sunyer
33.	Pathophysiology and Treatment of Lipid 
Disorders in Diabetes	563
	Barbara V. Howard and Wm. James Howard
SECTION V: TREATMENT OF DIABETES MELLITUS	585
34.	General Approach to the Treatment of 
Diabetes Mellitus	587
	Ramachandiran Cooppan
35.	Education in the Treatment of Diabetes	597
	Richard S. Beaser, Katie Weinger, and Lisa M. Bolduc-Bissell
36.	Medical Nutrition Therapy	611
	Karen Hanson Chalmers
37.	Behavioral Research and Psychological Issues 
in Diabetes: Progress and Prospects	633
	Barbara J. Anderson, Ann E. Goebel-Fabbri, and 
Alan M. Jacobson
38.	Exercise in Patients with Diabetes Mellitus	649
	Jeanne H. Steppel and Edward S. Horton
39.	Principles of Insulin Therapy	659
	Alice Y. Y. Cheng and Bernard Zinman
40.	Iatrogenic Hypoglycemia	671
	Stephanie Anne Amiel
41.	Management of Hyperglycemia with Oral 
Antihyperglycemic Agents in Type 2 Diabetes	687
	Harold E. Lebovitz
42.	Treatment of the Child and Adolescent 
with Diabetes	711
	Lori Laffel, Cindy Pasquarello, and Margaret Lawlor
43.	Treatment of Older Adults with Diabetes	737
	Caroline S. Blaum and Jeffrey B. Halter
44.	Women's Health Issues in Diabetes Mellitus	747
	Julie Lund Sharpless
45.	Pancreas and Islet Transplantation	765
	Gordon C. Weir
46.	Diabetes and the Healthcare System: 
Economic and Social Costs	777
	James L. Rosenzweig
SECTION VI: BIOLOGY OF THE COMPLICATIONS OF DIABETES	793
47.	Epidemiology of Late Complications of Diabetes: 
A Basis for the Development and Evaluation of 
Preventive Programs	795
	Andrzej S. Krolewski and James H. Warram
48.	Relationship between Metabolic Control and 
Long-Term Complications of Diabetes	809
	David M. Nathan
49.	Mechanisms of Diabetic Microvascular 
Complications	823
	Christian Rask-Madsen, Zhiheng He, and George L. King
50.	Pathogenesis of Diabetic Neuropathy	839
	Phillip A. Low
51.	Pathogenesis of Diabetic Nephropathy	853
	Gabriella Gruden and GianCarlo Viberti
52.	Pathogenesis of Cardiovascular Disease in 
Diabetes	867
	Edward P. Feener and Victor J. Dzau
SECTION VII: DIABETIC COMPLICATIONS: CLINICAL ASPECTS	885
53.	Diabetic Ketoacidosis and Hyperosmolar 
Hyperglycemic State	887
	Jennifer Wyckoff and Martin J. Abrahamson
54.	Ocular Complications of Diabetes Mellitus	901
	Lloyd M. Aiello, Lloyd Paul Aiello, and Jerry D. Cavallerano
55.	Management of Diabetic Kidney Disease	925
	Mark E. Williams and Robert C. Stanton
56.	The Nervous System and Diabetes	951
	Roy Freeman
57.	Hypertension in Diabetes Mellitus	969
	Samy I. McFarlane, Jonathan Castro, Dmitri Kirpichnikov, 
and James R. Sowers
58. Diabetes Mellitus and Heart Disease	975
	Michael T. Johnstone and Richard Nesto
59.	Erectile Dsyfunction and Diabetes	999
	Ricardo Munarriz, Abdulmaged Traish, and Irwin Goldstein
60.	Infection and Diabetes	1017
	Deborah E. Sentochnik and George M. Eliopoulos
61.	Diabetes and Pregnancy	1035
	Florence M. Brown and Allison B. Goldfine
62.	Cutaneous Manifestations of Diabetes Mellitus	1049
	Mark H. Lowitt and Jeffrey S. Dover
63.	Joint and Bone Manifestations of Diabetes Mellitus	1061
	M. Elaine Husni, Susan F. Kroop, and Lee S. Simon
64.	Effects of Diabetes Mellitus on the Digestive 
System	1069
	Hiroshi Mashimo, Roger J. May , and Raj K. Goyal
65. Treatment of Diabetes in the Hospitalized Patient	1103
	Howard A. Wolpert
66.	The Diabetic Foot: Strategies for Treatment
and Prevention of Ulcerations	1111
	John M. Giurini
67.	Vascular Disease of the Lower Extremities 
in Diabetes Mellitus: Etiology and Management	1123
	Cameron M. Akbari and Frank W. LoGerfo
68.	Diabetes Mellitus and Wound Healing	1133
	Parham A. Ganchi and Elof Eriksson
SECTION VIII: HYPOGLYCEMIA AND ISLET CELL TUMORS	1145
69.	Hypoglycemia	1147
	Benjamin Glaser and Gil Leibowitz
70.	Endocrine Tumors of the Pancreas	1177
	Maha T. Barakat, Houman Ashrafian, and Stephen R. Bloom
Index1189
  Deceased.
# CONTENTS
 Deceased.

Library of Congress Subject Headings for this publication:

Diabetes.