Table of contents for Molecular diagnostics : for the clinical laboratorian / edited by William B. Coleman and Gregory J. Tsongalis.

Bibliographic record and links to related information available from the Library of Congress catalog.

Note: Contents data are machine generated based on pre-publication provided by the publisher. Contents may have variations from the printed book or be incomplete or contain other coding.


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Contents
Dedication 	v
Foreword 	vii
Preface 	xi
Contributors 	v
Part I. 	Introduction
1 	An Historical Perspective on the Clinical Diagnostic Laboratory	xxx
Robert E. Moore
Part II. 	Basic Molecular Biology
2 	An Overview of Nucleic Acid Biochemistry, Structure, and Function: 
The Foundations of Molecular Biology	xxx
William B. Coleman 
3 	Extraction of Nucleic Acids	xxx
Paul N. Bogner and Anthony A. Killeen
4 	Nucleic Acid Blotting Techniques: Theory and Practice	xxx
Terry Amiss and Sharon Collins Presnell 
5 	The Polymerase Chain Reaction	xxx
William B. Coleman and Gregory J. Tsongalis
6 	Bioinformatics: Computer-Based Approaches to Genetic Analysis
Sharon L. Ricketts
Part III. 	Molecular Diagnostic Technologies
7 	PCR-Based Methods for Mutation Detection	xxx
Ian M. Frayling, Emma Monk, and Rachel Butler
8 	Alternative Methods for Amplified Nucleic Acid Testing
Deborah A. Payne
9 	Electrophoretic Methods for Mutation Detection and DNA Sequencing
W. Edward Highsmith Jr.
10 	Single Nucleotide Polymorphisms: Testing DNA Variation for Disease 
Association
Ulrich Broeckel and Martin J. Hessner
11 	Microarray Approaches to Gene Expression Analysis	xxx
David Neil Hayes and Matthew Meyerson
12 	Methods for Analysis of DNA Methylation	xxx
Alexander Dobrovric 
Part IV. 	Other Clinical Diagnostic Technologies
13 	Flow Cytometry	xxx
Jospeh A. DiGiuseppe
14 	Medical Cytogenetics	xxx
Martha B. Keagle
15 	Fluorescence In Situ Hybridization: A Major Milestone in Luminous 
Cytogenetics	xxx
Suneel D. Mundle and Robert J. Koska
16 	Immunohistochemistry	xxx
John Hunt, Larissa Davydova, Richard W. Cartun, and Maria 
Baiulescu
17 	Laser Capture Microdissection	xxx
C. Robert Bagnell Jr. 
Part V. 	Quality Assurance in the Molecular Diagnostics 
Laboratory
18 	Framework for Quality Assurance Principles	xxx
Marlene Sabbath-Solitaire, Selwyn J. Baptist, and Teresita 
Cuyegkeng Redondo 
19 	Verification of Molecular Assays 	xxx
Brent L. Seaton
20 	Standards and Standardization of Molecular Diagnostics	xxx
John P. Jakupciak and Catherine O'Connell
21 	Laboratory-Developed Assays in Molecular Diagnostics	xxx
Andrea Ferreira-Gonzalez and Carleton T. Garrett
Part VI. 	Applications of Molecular Diagnostics for Genetic 
Diseases
22 	An Overview of Molecular Genetics
Elaine Weidenhammer and Gregory J. Tsongalis
23 	Genetic Basis of Neurologic and Neuromuscular Diseases 	xxx
Narasimhan Nagan, Christopher J. Klein, D. Brian Dawson, Myra J. 
Wick, and Stephen N. Thibodeau 
24 	Molecular Mechanisms of Endocrine Disorders	xxx
Amy Potter and John A. Phillips III
25 	Molecular Pathogenesis of Cardiovascular Disease	xxx
Alan H. B. Wu
26 	Molecular Diagnostics in Coagulation	xxx
Enrique Ballesteros
27 	Cystic Fibrosis	xxx
Eugene H. Lewis III, Myra J. Lewis, Jean A. Amos, and Gregory J. 
Tsongalis
28 	Prenatal Genotyping for Identification of Fetuses at Risk 
for Immune Cytopenic Disorders	xxx
Martin J. Hessner and Brian R. Curtis
29 	Personalized Medicine	xxx
Karen McCullough
Part VII. 	Applications of Molecular Diagnostics for Human 
Cancers
30 	Molecular Pathogenesis of Human Cancer	xxx
William B. Coleman and Gregory J. Tsongalis
31 	Application of Molecular Diagnostics to Hereditary Nonpolyposis 
Colorectal Cancer	xxx
Ian M. Frayling, Lisa Happerfield, Christopher Mattocks, Kim 
Oakhill, 
and Mark J. Arends
32 	Molecular Genetic Applications to the Diagnosis of Lymphoma	xxx
William N. Rezuke and Gregory J. Tsongalis
33 	Molecular Genetic Abnormalities in Acute and Chronic Leukemias	xxx
Pei Lin and L. Jeffrey Medeiros
Part VIII. 	Applications of Molecular Diagnostics for 
Infectious Diseases
34 	Molecular Testing for Chlamydia trachomatis and Neisseria 
gonorrhoeae	xxx
Alexandra Valsamakis
35 	Human Papillomavirus	xxx
Theresa M. Voytek and Gregory J. Tsongalis
36 	Molecular Diagnosis for HIV-1	xxx
Angela M. Caliendo and Charles E. Hill
37 	Hepatitis C	xxx
D. Robert Dufour
38 	Molecular Biology of CMV	xxx
Angela M. Caliendo and Nell S. Lurain
Part IX. 	Applications of Molecular Diagnostics for Identity-
Based Testing
39 	HLA Typing Using Molecular Methods	xxx
John L. Schmitz
40 	Molecular Analysis for Forensic Casework and Parentage Testing	xxx
Tracey C. Dawson
41 	Molecular Assessment of Bone Marrow Transplant Engraftment	xxx
Jessica K. Booker
42 	The Use of DNA-Based Identity Testing for Specimen Identification 	xxx
Andrew Ricci Jr. and Gregory J. Tsongalis
Part X. 	Issues for the Clinical Molecular Pathology Laboratory
43 	Genetic Counseling Considerations in Molecular Diagnosis	xxx
Myra I. Roche
44 	Ethical, Social, and Legal Issues Related to Molecular Genetic Testing	xxx
Jennifer L. Herbst and Jon F. Merz
Index	xxx

Library of Congress Subject Headings for this publication:

Molecular diagnosis.
Pathology, Molecular.