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Contents List of Contributors Preface to the First Edition Preface to the Second Edition Preface to the Third Edition Tribute List of Abbreviations SECTION I Scientific Basis for Hematopoietic Cell Transplantation 1. A History of Bone Marrow Transplantation (BMT), 000 E. Donnall Thomas 2. Uses and Growth of Hematopoietic Cell Transplantation, 000 Mary M. Horowitz 3. Overview of Hematopoietic Cell Transplantation Immunology, 000 Paul J. Martin 4. Histocompatibility, 000 Eric Mickelson & Effie W. Petersdorf 5. Functional Evolution of the Major Histocompatibility Complex, 000 Lakshmi K. Gaur 6. Mechanisms of Human Hematopoiesis, 000 Catherine M. Verfaillie 7. Molecular Aspects of Stem Cell Renewal, 000 Peter M. Lansdorp 8. Isolation and Characterization of Hematopoietic and Lymphopoietic Cells, 000 Markus Manz, Koichi Akashi & Irving L. Weissman 9. Expansion of Hematopoietic Stem Cells, 000 Colleen Delaney, Robert Andrews & Irwin Bernstein 10. Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells, 000 Thomas Moritz & David A. Williams 11. Genetic Marking and Clinical Trials of Gene Therapy Using Hematopoietic Stem Cells, 000 Donald B. Kohn & Gay M. Crooks 12. Pharmacological Basis for High-Dose Chemotherapy, 000 James H. Doroshow & Timothy Synold 13. Preparatory Regimens and Modification of Regimen-Related Toxicities, 000 William I. Bensinger & Ricardo Spielberger 14. Radiotherapeutic Principles in Hematopoietic Cell Transplantation, 000 Brenda M. Shank & Richard T. Hoppe 15. Radioimmunotherapy and Hematopoietic Cell Transplantation, 000 Dana C. Matthews & Frederick R. Appelbaum 16. Pharmacology and Use of Immunosuppressive Agents After Hematopoietic Cell Transplant, 000 Nelson J. Chao 17. T-Cell Depletion for the Prevention of Graft-Versus-Host Disease, 000 Robert Soiffer 18. Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation, 000 Eileen Bryant & Paul J. Martin 19. Antibody-Mediated Purging, 000 John G. Gribben 20. Pharmacologic Purging of Bone Marrow, 000 O. Michael Colvin 21. Molecular Inhibition of Gene Expression in Hematopoietic Cells, 000 Joanna B. Opalinska & Alan M. Gewirtz 22. The Detection and Significance of Minimal Residual Disease, 000 Jerald P. Radich & Marilyn L. Slovak 23. Pathology of Hematopoietic Cell Transplantation, 000 George E. Sale, Howard M. Shulman & Robert C. Hackman 24. Mechanisms of Tolerance, 000 Megan Sykes 25. The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases, 000 Judith A. Shizuru 26. Murine Models for Graft-Versus-Host Disease, 000 Robert Korngold & Thea M. Friedman 27. The Pathophysiology of Graft-Versus-Host Disease, 000 James L.M. Ferrara & Joseph H. Antin 28. Graft-Versus-Tumor Responses, 000 Alexander Fefer 29. Adoptive Immunotherapy with Antigen-Specific T Cells, 000 Stanley R. Riddell & Philip D. Greenberg 30. Autologous Graft-Versus-Host Disease, 000 Allan D. Hess & Richard J. Jones 31. Biostatistical Methods in Hematopoietic Cell Transplantation, 000 Joyce C. Niland 32. Outcomes Research in Hematopoietic Cell Transplantation, 000 Stephanie J. Lee SECTION II Patient Related Issues in Hematopoietic Cell Transplantation 33. The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation, 000 Karl G. Blume & Michael D. Amylon 34. Case Management of Hematopoietic Cell Transplant Patients, 000 Laura L. Adams & Angela A. Johns 35. Nursing Issues in Hematopoietic Cell Transplantation, 000 Rosemary C. Ford, Judy Campbell & Juanita Madison 36. The Patient's Perspective, 000 Susan K. Stewart 37. Ethical Issues in Hematopoietic Cell Transplantation, 000 David S. Snyder 38. Psychological Issues in Hematopoietic Cell Transplantation, 000 Michael A. Andrykowski & Richard P. McQuellon 39. Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients, 000 Karen Syrjala 40. Sexuality After Hematopoietic Cell Transplantation, 000 D. Kathryn Tierney SECTION III Sources of Hematopoietic Cells for Human Transplant 41. Guidelines for the Procurement and Manipulation of Stem Cells for Transplantation, 000 Phyllis I. Warkentin, Lewis Nick & Elizabeth J. Shpall 42. Bone Marrow and Peripheral Blood Stem Cell Donors, 000 Dennis L. Confer 43. Cord Blood Stem Cell Transplantation, 000 Hal E. Broxmeyer & Franklin O. Smith 44. In Utero Transplantation, 000 Alan W. Flake & Esmail D. Zanjani 45. Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy, 000 Thomas Shea 46. Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation, 000 Norbert Schmitz 47. Cryopreservation of Hematopoietic Cells, 000 Scott D. Rowley 48. Use of Recombinant Growth Factors After Hematopoietic Cell Transplantation, 000 Jurgen Finke & Roland Mertelsmann 49. Hematopoietic Cell Donor Registries, 000 Jeffrey Chell SECTION IV Complications and Their Management 50. Graft-Versus-Host Disease, 000 Keith M. Sullivan 51. Bacterial Infections, 000 John R. Wingard & Helen L. Leather 52. Fungal Infections, 000 Janice M. Brown 53. Cytomegalovirus Infections, 000 John A. Zaia 54. Herpes Simplex Virus Infections, 000 James Ito 55. Varicella-Zoster Virus Infections, 000 Ann M. Arvin 56. Epstein-Barr Virus Infection, 000 Richard F. Ambinder 57. Other Viral Infections after Hematopoietic Cell Transplantation, 000 Michael Boeckh 58. Gastrointestinal and Hepatic Complications, 000 Simone I. Strasser & George B. McDonald 59. Neurological Complications, 000 Harry Openshaw 60. Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation, 000 Margaret R. O'Donnell 61. Principles of Transfusion Support Before and After Hematopoietic Cell Transplantation, 000 Jeffrey McCullough 62. Immunological Reconstitution Following Hematopoietic Stem Cell Transplantation, 000 Robertson Parkman & Kenneth I. Weinberg 63. Vaccination of Hematopoietic Cell Transplant Recipients, 000 Claire Dykiewicz 64. Critical Care and Respiratory Failure, 000 David Horak 65. Nutritional Support of Hematopoietic Cell Transplant Recipients, 000 Sally S. Weisdorf Schindele & Sarah J. Schwarzenberg 66. Pain Management, 000 Jonathan R. Gavrin & F. Peter Buckley 67. Oral Complications, 000 Mark M. Schubert, Douglas E. Peterson & Michele E. Lloid 68. Growth and Development After Hematopoietic Cell Transplantation, 000 Jean E. Sanders 69. Delayed Complications After Hematopoietic Cell Transplantation, 000 Mary E.D. Flowers & H. Joachim Deeg 70. Secondary Malignancies after Hematopoietic Cell Transplantation, 000 Smita Bhatia & Ravi Bhatia SECTION V Allogeneic Transplantation for Acquired Diseases 71. Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia, 000 George E. Georges & Rainer Storb 72. Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria, 000 Robert P. Witherspoon 73. Allogeneic Transplantation for Chronic Myeloid Leukemia, 000 Frederick R. Appelbaum 74. Allogeneic Cell Transplantation for Juvenile Myelomonocytic Leukemia, 000 Robert A. Krance 75. Allogeneic Transplantation for Adult Patients with Acute Myeloid Leukemia, 000 Keith E. Stockerl-Goldstein & Karl G. Blume 76. Allogeneic Transplantation for Acute Myeloid Leukemia in Children, 000 David A. Margolis & James T. Casper 77. Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Adults, 000 Stephen J. Forman 78. Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children, 000 Stella M. Davies, Norma K.C. Ramsay & John H. Kersey 79. Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders, 000 Jeanne E. Anderson 80. Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma, 000 David G. Maloney & Gösta Gahrton 81. Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia, 000 Richard Champlin & Issa Khouri 82. Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors, 000 Claudio Anasetti & Andrea Velardi 83. Hematopoietic Cell Transplantation from Unrelated Donors, 000 Effie W. Petersdorf 84. Management of Relapse After Allogeneic Transplantation, 000 Robert Collins 85. Non-Myeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders, 000 Brenda M. Sandmaier & Rainer Storb 86. Non-Myeloablative Therapy and Hematopoietic Cell Transplantation for Solid Tumors, 000 Richard Childs SECTION VI Autologous Transplantation for Acquired Diseases 87. Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin Disease, 000 Auayporn P. Nademanee & Philip J. Bierman 88. Autologous Hematopoietic Cell Transplantation for non-Hodgkin Lymphoma, 000 Sandra J. Horning & James O. Armitage 89. Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia, 000 Anthony S. Stein & Stephen J. Forman 90. Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia, 000 Charles Linker 91. Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia, 000 Ravi Bhatia & Philip B. McGlave 92. Autologous Hematopoietic Cell Transplantation for Multiple Myeloma, 000 Kenneth Anderson 93. Autologous Hematopoietic Cell Transplantation for AL Amyloidosis, 000 Raymond L. Comenzo & Morie Gertz 94. Autologous Hematopoietic Cell Transplantation for Breast Cancer, 000 Karen H. Antman 95. Autologous Hematopoietic Cell Transplantation in Germ Cell Tumors, 000 Craig R. Nichols 96. Autologous Hematopoietic Cell Transplantation for Ovarian Carcinoma, 000 Patrick J. Stiff 97. Hematopoietic Cell Transplantation for Neuroblastoma, 000 Kathryn K. Matthay 98. Hematopoietic Cell Transplantation for Brain Tumors, 000 Ira J. Dunkel & Jonathan L. Finlay 99. Hematopoietic Cell Transplantation for Pediatric Solid Tumors, 000 Allen R. Chen & Curt I. Civin 100. Genetic Modification and Transplantation of Hematopoietic Cells for Treatment of Human Immunodeficiency Virus Infection, 000 John A. Zaia 101. Hematopoietic Cell Transplantation for Autoimmune Diseases, 000 Alan Tyndall & Alois Gratwohl 102. Prevention and Therapy of Relapse After Autologous Hematopoietic Cell Transplantation, 000 Robert S. Negrin SECTION VII Allogeneic Transplantation for Inherited Diseases 103. Marrow Transplantation in Thalassemia, 000 Guido Lucarelli & Reginald A. Clift 104. Hematopoietic Cell Transplantation for Sickle Cell Disease, 000 Mark C. Walters 105. Hematopoietic Cell Transplantation for Immunodeficiency Diseases, 000 Trudy N. Small, Wilhelm Friedrich & Richard J. O'Reilly 106. Hematopoietic Cell Transplantation for Osteopetrosis, 000 Peter F. Coccia 107. Hematopoietic Cell Transplantation for Storage Diseases, 000 Charles Peters 108. Hematopoietic Cell Transplantation for Granulocyte and Macrophage Disorders, 000 Rajni Agarwal 109. Hematopoietic Cell Transplantation in the Treatment of Fanconi Anemia, 000 John E. Wagner, Margaret M. McMillan & Arleen D. Auerbach SECTION VIII The Future 110. Stem Cell Transplantation in the Twenty-First Century, 000 Ernest Beutler SECTION IX Colorplates, facing page 000 Robert C. Hackman Index, 000
Library of Congress Subject Headings for this publication: Hematopoietic stem cells Transplantation, Hematopoietic Stem Cell Transplantation, Transplantation Immunology