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CONTENTS Preface v Contributors ix Part I. Historical Perspective 1. Portal Hypertension: A History Adrian Reuben and Roberto J. Groszmann xx Part II. Pathobiology and Experimental Progress in Portal Hypertension 2. Anatomy and Vascular Biology of the Cells in the Portal Circulation Massimo Pinzani and Francesco Vizzutti xx 3. Cell and Molecular Mechanisms of Increased Intrahepatic Resistance and Hemodynamic Correlates Don C. Rockey xxx 4. Molecular Mechanisms of Systemic Vasodilation and Hyperdynamic Circulatory State of Cirrhosis Richard Moreau and Didier Lebrec xxx 5. Mechanisms of Sodium Retention, Ascites Formation, and Renal Dysfunction in Cirrhosis Andrés Cardenas and Pere Ginès xxx 6. Hepatic Hemodynamics in Portal Hypertension: Compliance, Hepatic Arterial Buffer Response, Hepatorenal Syndrome, and Liver Regeneration W. Wayne Lautt and Zhi Ming xxx 7. Neovascularization, Angiogenesis and Vascular Remodeling in Portal Hypertension Manuel Morales-Ruiz and Wladimiro Jiménez xxx 8. Mechanisms of Cardiopulmonary Hemodynamics and Dysfunction in Portal Hypertension Michael B. Fallon xxx Part III: Methodology to Assess Portal Hypertension in Humans 9. Measurement of Hepatic Venous Pressure Gradient: Methods, Iinterpretation, and Pitfalls G. Pomier-Layrargues and P. Michel Huet xxx 10. Evaluation of Portal Hemodynamics Using Indicator Dilution and Noninvasive Techniques Juerg Reichen xxx 11. Endoscopic Assessment of Portal Hypertension Including Variceal Pressure Measurement: Methods, Interpretation and Pitfalls Angel Escorsell and Jaime Bosch xx Part IV: Natural History and Treatment of Esopheageal Varices 12. Clinical Features and Natural History of Variceal Hemorrhage: Implications for Surveillance and Screening Juan G. Abraldes and Jaime Bosch xxx 13. Management Strategies for the Prophylaxis and Treatment of Esophageal Variceal Rupture: An Overview Roberto de Franchis xxx 14. Pharmacologic Therapy for the Management of Esophageal Varices: Biology and Utility of Available Agents Norman Grace and Richard S. Tilson xxx 15. Endoscopic Treatment for Bleeding Esophageal Varices John P. Cello xxx 16. Surgical Therapies for Management: Surgical Shunts and Liver Transplantation J. Michael Henderson xxx 17. Transjugular Intrahepatic Portasystemic Stent-Shunt: Technical Considerations and Clinical Utility in the Management of Variceal Hemorrhage Dhiraj Tripathi, Peter C. Hayes, Doris N. Redhead, and Rajiv Jalan xxx 18. Clinical Features and Management of Gastric Varices, Portal Hypertensive Gastropathy, and Ectopic Varices Charmaine A. Stewart and Patrick S. Kamath xxx Part V: Natural History and Treatment of Ascites and Hepatorenal Syndrome 19. Ascites: Clinical Features, Diagnosis and Natural History Sakib Karim Khalid and Guadalupe Garcia-Tsao xxx 20. Management of Ascites Florence Wong xxx 21. Spontaneous Bacterial Peritonitis and Other Infections in Cirrhosis Rosa Maria Morillas and Ramon Planas xxx 22. Diagnosis and Management of Hepatorenal Syndrome Kevin Moore xxx Part V: Evaluation and Treatment in Special Circumstances of Portal Hypertension 23. Pregnancy and Portal Hypertension Bimaljit Sandhu and Arun J. Sanyal xxx 24. Causes and Management of Portal Hypertension in the Pediatric Population Frederick C. Ryckman, Maria H. Alonso, and Greg Tiao xxx 25. Noncirrhotic Portal Hypertension and Portal Vein Thrombosis Shiv Sarin and Manav Wadhavan xxx 26. Hepatic Venous Outflow Obstruction: Budd-Chiari Syndrome and Veno-Occlusive Disease Hugo E. Vargas and Thomas D. Boyer xxx 27. Pulmonary Complications Associated with Portal Hypertension Karen L. Swanson and Michael J. Krowka xxx 28. Health Status Assessment and Economic Analyses in Cirrhosis and Portal Hypertension Jayant A. Talwalkar and W. Ray Kim xxx 29. Future Treatments: Anti-Fibrotic Agents, Nitric Oxide Donors, and Gene Therapy in the Treatment of Portal Hypertension Meena B. Bansal and Scott L. Friedman xxx Index xxx
Library of Congress Subject Headings for this publication:
Portal hypertension.
Hypertension, Portal.