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CONTENTS Preface Acknowledgments Introduction 1 Common Types of Cancer Terminology Bladder Cancer Brain Tumors Breast Cancer Leukemia Lung Cancer Prostate Cancer Skin Cancer 2 Cancer Cells Cancer Cells are Immortal Broken Chromosomes A Failure to Communicate They Go Where They Please One Mutation Is Not Enough 3 The Road to Oncogenesis Cancer and the Cell Cycle A Disease of the Genes Tumor Suppressor Genes Oncogenes and Proto-oncogenes A Dangerous Mix 4 Cancer Progression Cancers Develop from a Single Bad Cell The Switch From Benign to Malignant Tumors The Role of Sex Hormones Aging and the Incidence of Cancer Carcinogens 5 Cancer Therapies Angiogenesis Blockers Biotherapies Bone Marrow Transplants Chemotherapy Cryosurgery Gene Therapy Laser Therapy Photodynamic Therapy Radiotherapy Stem Cell Therapy 6 Cancer Around the World The Magnitude of the Problem Developed Countries Have the Highest Cancer Rates Cancer and the North American Diet Cancer and Lifestyle Cancer and the Environment Summary 7 Clinical Trials The Four Phases Breast Cancer Chemotherapy Colon Cancer Lung Cancer Melanoma Metastasis 8 Resource Center Eucaryote Cell Primer Recombinant DNA Primer Gene Therapy Primer Matching Tissues The Human Genome Project APPENDIXES Glossary Further Reading Websites Index
Library of Congress Subject Headings for this publication: Cancer Social aspects, Cancer Environmental aspects, Cancer Genetic aspects