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1. Introduction 2. Practice, reason, context: the dialogue between theory and experiment 3. The discipline of nature and the nature of disciplines 3. The discipline of nature and the nature of disciplines 4. Social interests and the organic physics of 1847 5. Science for the clinic: science policy and the formation of Carl Ludwig's Institute in Leipzig 6. The politics of vision optics, painting, and ideology in Germany 1845-95 7. A magic bullet: research for profit and the growth of knowledge in Germany around 1900 8. Practical reason and the construction of knowledge: the lifeworld of Haber-Bosch 9. Instrument makers and discipline builders: the case of nuclear magnetic resonance Notes Index.