Publisher description for BCL-2 protein family : essential regulators of cell death / edited by Claudio Hetz.

Bibliographic record and links to related information available from the Library of Congress catalog

Information from electronic data provided by the publisher. May be incomplete or contain other coding.

In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.

Library of Congress subject headings for this publication:
Tumor proteins.
Proto-Oncogene Proteins c-bcl-2 -- metabolism.
Proto-Oncogene Proteins c-bcl-2 -- physiology.
Apoptosis -- physiology.
Neoplasms -- metabolism.
Neoplasms -- pathology.