Publisher description for Bioinformatics and biomarker discovery : "omic" data analysis for personalised medicine / Francisco Azuaje.

Bibliographic record and links to related information available from the Library of Congress catalog

Information from electronic data provided by the publisher. May be incomplete or contain other coding.

Bioinformatics and Biomarker Discovery: “Omic” Data Analysis for Personalised Medicine_is designed to introduce biologists, clinicians and computational researchers to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and the implementation of diagnostic/prognostic systems.
The focus of the book is on how fundamental statistical and data mining approaches can support biomarker discovery and evaluation, emphasising applications based on different types of “omic” data. The book also discusses design factors, requirements and techniques for disease screening, diagnostic and prognostic applications.
Readers are provided with the knowledge needed to assess the requirements, computational approaches and outputs in disease biomarker research. Commentaries from guest experts are also included, containing detailed discussions of methodologies and applications based on specific types of “omic” data, as well as their integration._ Covers the main range of data sources currently used for biomarker discovery
Puts emphasis on concepts, design principles and methodologies that can be extended or tailored to more specific applications

Offers principles and methods for assessing the bioinformatic/biostatistic limitations, strengths and challenges in biomarker discovery studies

Discusses systems biology approaches and applications

Includes expert chapter commentaries to further discuss relevance of techniques, summarise biological/clinical implications and provide alternative interpretations

Library of Congress subject headings for this publication:
Biochemical markers.
Computational Biology.
Biological Markers.
Genomics -- methods.
Statistics as Topic.