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Drawing from synthetic chemistry, molecular modeling, computational biology, structural genomics, and pharmacology, this text fully explores medicinal chemistry. With a chemical-molecular perspective, it focuses on the correlation of properties and biological activity, and delves into the phenomenon of xenobiotic metabolism. Written by experts representing various research fields, Medicinal Chemistry addresses current epidemiological, scientific, social, and economic concerns, and considers approaches to Alzheimer's, HIV, addiction, and environmental chemical toxicity, as well as cardiovascular, psychological, and neurological disorders. It also examines approaches to rational drug design.