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Biocatalysis in the Pharmaceutical and Biotechnology Industries illustrates the practical advantages and methodologies for using biocatalysts to develop and produce chiral intermediates and fine chemicals. The book analyzes syntheses for over 60 brand-name pharmaceuticals, offering detailed mechanisms that show chiral intermediates and other by-products for each modification. Focusing on industrial applications, the book describes instrumentation, solvent selection, and techniques in enzyme immobilization. It also highlights recent developments such as the directed evolution of biocatalysts, gene shuffling, the use of microbial cells and isolated biocatalysts, and generating novel molecules for high-throughput screening. The book contains over 4000 references and more than 1000 tables, equations, drawings, and color micrographs.