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Particle Toxicology integrates the current knowledge in particulate physico-chemistry, cell/molecular biology and toxicology into a single volume. While using the classical toxicology paradigm of exposure - dose - response, it provides reviews on the mechanisms and properties of pathogenic particles and their pathogenic effects. The text describes how these actions may be related to specific site of deposition, translocation, particle composition, shape and the outcome of various pathogenic processes involving pro-inflammatory effects and inflammatory signaling, oxidative and nitrosative stress, particulate interactions in the pulmonary, cardiovascular, and central nervous systems, as well as genotoxic effects of ultrafine and other particles.