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This symposium brought together atomic physicists, nuclear physicists, astronomers, and astrophysicists from around the world to focus on stellar atmospheres, stellar evolution, stellar explosions (novae, supernovae, and X-ray bursters), pregalactic and galactic chemical evolution, the interstellar medium, and atomic and nuclear data for astrophysics. Consisting of invited papers, invited posters, and contributed posters, this proceedings covers observations, modeling, and the atomic and nuclear physics foundations (data, experiments, and theories) essential to understanding these important astrophysical objects and events. It documents a confluence of atomic physics, nuclear physics, and astrophysics, and a confluence of data from atomic and nuclear physics experiments from current-generation astronomical instruments, that have helped advance the frontier in our understanding of the Universe.