Publisher description for Assessing bioavailability of drug delivery systems : mathematical and numerical treatment / Jean-Maurice Vergnaud, Iosif-Daniel Rosca.

Bibliographic record and links to related information available from the Library of Congress catalog

Information from electronic data provided by the publisher. May be incomplete or contain other coding.


This book introduces mathematical modeling methods for calculating the profiles of plasma levels obtained with controlled release dosage forms and provides examples and case studies to illustrate the techniques employed. The mathematical models developed by the author are particularly powerful because they account for such major parameters as the kinetics of drug release controlled by diffusion or by erosion, and the kinetics of absorption into and elimination out of the plasma. They are also able to solve the problem of determining the drug level in plasma as a result of patient non-compliance, incorrect dosage, and incorrect frequency, and to determine the best dosage forms necessary for therapy.

Library of Congress subject headings for this publication:
Drugs -- Dosage forms -- Mathematics.
Drugs -- Dosage forms -- Statistical methods.