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The Process of New Drug Discovery and Development, Second Edition presents a practical methodology and up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. This new edition reports on the scientific advances in new drug discovery and development for areas such as combinatorial chemistry, screening technologies, metabonomics, and preclinical testing. It also greatly expands its focus on the business aspects of bringing drugs to market and offers coverage of essential topics for companies involved in drug development, such as the financial aspects of establishing a start-up pharmaceutical enterprise, the regulatory process, risk assessment, liability and litigation, and patent law.