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Incorporating new information, the authors provide a uniquely cohesive exploration of environmental stress in arthropods, specifically Drosophila, that fills previous gaps in the literature. They cover topics ranging from disturbance of homeostasis, changes in metabolic processes, and damage of cellular structures, to acquired tolerance, effects on aging processes, and survival and cell death. By analyzing these aspects in detail at the molecular, biochemical, and physiological level of the cell, readers get a thorough look at the relationship between an organism and its environment at the cellular level. The book also introduces the recently emerging concept of integrated stress response.