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The core text and standard reference in toxicology has once again been updated to incorporate the latest testing procedures and address new challenges faced by toxicologists. The author brings together more than 70 distinguished investigators to detail current testing procedures, offer guidelines on data interpretation and highlight major areas of controversy. The book deals with the methods of toxicology, as well as principles and agents. New chapters on exposure assessment and epidemiology for toxicologists have been added. Principles and Methods of Toxicology, Fourth Edition allows the working toxicologist, whether a senior professional or graduate student, to understand and use basic experiments.