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Mark D. Miller, M.D., is an associate professor of psychiatry at the University of Pittsburgh School of Medicine and medical director of the Late-Life Depression Prevention Clinic at the Western Psychiatric Institute and Clinic. Charles F. Reynolds III, M.D., is a professor of psychiatry, neurology, and neuroscience at the University of Pittsburgh School of Medicine, where he is also director of the NIMH-funded Intervention Research Center for Late-Life Mood Disorders.